Jean-Emmanuel Hugonnet : rechercher sur Z-Library

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1

Activation of the l,d-transpeptidation peptidoglycan cross-linking pathway by a metallo-d,d-carboxypeptidase in Enterococcus faecium

Emmanuelle Sacco, Jean-Emmanuel Hugonnet, Nathalie Josseaume, Julie Cremniter, Lionel Dubost, Arul Marie, Delphine Patin, Didier Blanot, Louis B. Rice, Jean-Luc Mainardi, Michel Arthur

Journal:

Molecular Microbiology

Année:

2010

Langue:

english

Fichier:

PDF, 452 KB

english, 2010

2

Dynamics Induced by β-Lactam Antibiotics in the Active Site of Bacillus subtilis l,d-Transpeptidase

Lauriane Lecoq, Catherine Bougault, Jean-Emmanuel Hugonnet, Carole Veckerlé, Ombeline Pessey, Michel Arthur, Jean-Pierre Simorre

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2012

3

Crystal Structure of a Novel β-Lactam-insensitive Peptidoglycan Transpeptidase

Sabrina Biarrotte-Sorin, Jean-Emmanuel Hugonnet, Vanessa Delfosse, Jean-Luc Mainardi, Laurent Gutmann, Michel Arthur, Claudine Mayer

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 358 KB

english, 2006

4

Discovery of the first inhibitors of bacterial enzyme d-aspartate ligase from Enterococcus faecium (Aslfm)

Škedelj, Veronika, Perdih, Andrej, Brvar, Matjaž, Kroflič, Ana, Dubbée, Vincent, Savage, Victoria, O'Neill, Alex J., Solmajer, Tom, Bešter-Rogač, Marija, Blanot, Didier, Hugonnet, Jean-Emmanuel, Magne

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.58 MB

english, 2013

5

Structure of the Covalent Adduct Formed between Mycobacterium tuberculosis β-Lactamase and Clavulanate †‡

Tremblay, Lee W., Hugonnet, Jean-Emmanuel, Blanchard, John S.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 2.27 MB

english, 2008

6

Structure of Enterococcus faecium l , d -Transpeptidase Acylated by Ertapenem Provides Insight into the Inactivation Mechanism

Lecoq, Lauriane, Dubée, Vincent, Triboulet, Sébastien, Bougault, Catherine, Hugonnet, Jean-Emmanuel, Arthur, Michel, Simorre, Jean-Pierre

Journal:

ACS Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 2.85 MB

english, 2013

7

Irreversible Inhibition of the Mycobacterium tuberculosis β-Lactamase by Clavulanate †

Hugonnet, Jean-Emmanuel, Blanchard, John S.

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 110 KB

english, 2007

8

Rapid Cytolysis of Mycobacterium tuberculosis by Faropenem, an Orally Bioavailable β-Lactam Antibiotic

Dhar, Neeraj, Dubée, Vincent, Ballell, Lluis, Cuinet, Guillaume, Hugonnet, Jean-Emmanuel, Signorino-Gelo, François, Barros, David, Arthur, Michel, McKinney, John D.

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.98 MB

english, 2015

9

Impact of β-Lactamase Inhibition on the Activity of Ceftaroline against Mycobacterium tuberculosis and Mycobacterium abscessus

Dubée, Vincent, Soroka, Daria, Cortes, Mélanie, Lefebvre, Anne-Laure, Gutmann, Laurent, Hugonnet, Jean-Emmanuel, Arthur, Michel, Mainardi, Jean-Luc

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 453 KB

english, 2015

10

The mutation landscape of acquired cross-resistance to glycopeptide and β-lactam antibiotics in Enterococcus faecium

Sacco, Emmanuelle, Cortes, Mélanie, Josseaume, Nathalie, Bouchier, Christiane, Dubée, Vincent, Hugonnet, Jean-Emmanuel, Mainardi, Jean-Luc, Rice, Louis B, Arthur, Michel

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2015

11

Hydrolysis of clavulanate by Mycobacterium tuberculosis β-lactamase BlaC harboring a canonic SDN motif

Soroka, Daria, Li de la Sierra-Gallay, Inès, Dubée, Vincent, Triboulet, Sébastien, van Tilbeurgh, Herman, Compain, Fabrice, Ballell, Lluis, Barros, David, Mainardi, Jean-Luc, Hugonnet, Jean-Emmanuel,

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

12

Handbook of Proteolytic Enzymes || l,d-Transpeptidase (Enterococcus)

Hugonnet, Jean-Emmanuel

Année:

2013

Langue:

english

Fichier:

PDF, 1015 KB

english, 2013

13

Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

Rullas, Joaquín, Dhar, Neeraj, McKinney, John D., García-Pérez, Adolfo, Lelievre, Joël, Diacon, Andreas H., Hugonnet, Jean-Emmanuel, Arthur, Michel, Angulo-Barturen, Iñigo, Barros-Aguirre, David, Ball

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 437 KB

english, 2015

14

Routes of Synthesis of Carbapenems for Optimizing Both the Inactivation of l , d -Transpeptidase Ldt Mt1 of Mycobacterium tuberculosis and the Stability toward Hydrolysis by β-Lactamase BlaC

Iannazzo, Laura, Soroka, Daria, Triboulet, Sébastien, Fonvielle, Matthieu, Compain, Fabrice, Dubée, Vincent, Mainardi, Jean-Luc, Hugonnet, Jean-Emmanuel, Braud, Emmanuelle, Arthur, Michel, Etheve-Quel

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2016

15

Acyl acceptor recognition by E nterococcus faecium l , d -transpeptidase Ldt fm

Triboulet, Sébastien, Bougault, Catherine M., Laguri, Cédric, Hugonnet, Jean-Emmanuel, Arthur, Michel, Simorre, Jean-Pierre

Journal:

Molecular Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 7.59 MB

english, 2015

16

Inhibition of β-lactamases of mycobacteria by avibactam and clavulanate

Soroka, Daria, Ourghanlian, Clément, Compain, Fabrice, Fichini, Marion, Dubée, Vincent, Mainardi, Jean-Luc, Hugonnet, Jean-Emmanuel, Arthur, Michel

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 351 KB

english, 2016

17

Peptidoglycan cross-linking activity of L,D-transpeptidases from Clostridium difficile and inactivation of theses enzymes by β-lactams

Sütterlin, Laetitia, Edoo, Zainab, Hugonnet, Jean-Emmanuel, Mainardi, Jean-Luc, Arthur, Michel

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 2.14 MB

english, 2017

18

Critical impact of peptidoglycan precursor amidation on the activity of L,D-transpeptidases from Enterococcus faecium and Mycobacterium tuberculosis

Ngadjeua, Flora, Braud, Emmanuelle, Saidjalolov, Saidbakhrom, Iannazzo, Laura, Schnappinger, Dirk, Ehrt, Sabine, Hugonnet, Jean-Emmanuel, Mengin-Lecreulx, Dominique, Patin, Delphine Patin, Ethève-Quel

Journal:

Chemistry - A European Journal

Année:

2018

Langue:

english

Fichier:

PDF, 2.00 MB

english, 2018

19

Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli

Hugonnet, Jean-Emmanuel, Mengin-Lecreulx, Dominique, Monton, Alejandro, den Blaauwen, Tanneke, Carbonnelle, Etienne, Veckerlé, Carole, Brun, Yves, V., van Nieuwenhze, Michael, Bouchier, Christiane, Tu

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.55 MB

english, 2016

20

Methicillin-Susceptible, Vancomycin-Resistant Staphylococcus aureus , Brazil

Panesso, Diana, Planet, Paul J., Diaz, Lorena, Hugonnet, Jean-Emmanuel, Tran, Truc T., Narechania, Apurva, Munita, Jose M., Rincon, Sandra, Carvajal, Lina P., Reyes, Jinnethe, Londoño, Alejandra, Smit

Journal:

Emerging Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 553 KB

english, 2015

21

Copper inhibits peptidoglycan LD-transpeptidases suppressing β-lactam resistance due to bypass of penicillin-binding proteins

Peters, Katharina, Pazos, Manuel, Edoo, Zainab, Hugonnet, Jean-Emmanuel, Martorana, Alessandra M., Polissi, Alessandra, VanNieuwenhze, Michael S., Arthur, Michel, Vollmer, Waldemar

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 937 KB

english, 2018